Jujiao Kang

KDRD: assessing discovery replicability based on summary association statistics from a single study

KDRD estimates replicability of associations using summary statistics from a single study, showing moderate to high replicability for 33 of 45 brain-related traits in proteomics analyses.

Merits and challenges of plasma proteomics on association replicability

The paper assesses the replicability of plasma proteomics associations with phenotypes using UK Biobank data, finding high replicability for cognitive and mental health traits and developing a framework to predict replicability in future panels.

Association between obesity, brain atrophy and accelerated brain aging and their genetic mechanisms

This study identifies a causal link between BMI and reduced grey matter volume, finds accelerated brain aging in obesity, and links it to gene expression changes in autophagy pathways.

Assessing Overall Reproducibility for Large-scale High-throughput MRI-based Association Studies

This study introduces an overall reproducibility index for MRI-based association studies and evaluates its performance across multiple datasets, showing that sample size and experimental factors influence reproducibility.