Merits and challenges of plasma proteomics on association replicability
Zeyu Jiao, Yixin Zhang, Yinglei Lai, Jujiao Kang, Liang Ma, Wei Zhao, Jia You, Wei Cheng, Jianfeng Feng
The paper assesses the replicability of plasma proteomics associations with phenotypes using UK Biobank data, finding high replicability for cognitive and mental health traits and developing a framework to predict replicability in future panels.
bioRxiv · Sep 1, 2025 · PreprintBioinformatics