Deborah Dean

The paper identifies four immune state types (ISTs) in trachoma patients using protein profiling, linking them to infection, inflammation, and scarring outcomes.

The paper introduces MetaChlam, a pipeline for strain typing Chlamydia trachomatis in metagenomes, showing it outperforms existing tools and detects contaminants.

The paper identifies ocular microbiome community state types (CSTs) in Ethiopian villagers, linking specific microbial compositions to trachoma prevalence and potential therapeutic implications.

The paper analyzes azithromycin resistance mutations in Chlamydia trachomatis genomes, finding common mutations in rplV that predate azithromycin's clinical use.

This study examines how azithromycin affects microbial composition, function, and resistance genes in endocervical, vaginal, and rectal microbiomes of women with Chlamydia trachomatis infection.

The paper improves whole-genome sequencing of Chlamydia trachomatis from clinical samples by redesigning an RNA bait library, achieving 100% efficiency and identifying genomic recombination in paired specimens.