Manabu Shiraishi

This study establishes a TAC-release model in rats to investigate the reversibility of cardiac hypertrophy and fibrosis, identifying Rcan1 as a key regulator.

This study investigates how cardiac fibroblasts respond to hemodynamic changes, identifying Selenbp1 as a key regulator of fibroblast differentiation and collagen turnover in cardiac fibrosis.

This study investigates how M2-like macrophages regulate post-MI fibrosis through Nrg1/ErbB signaling, showing it suppresses fibroblast senescence and apoptosis.