Statistical tests for bivariate spatial association across multi-omics data with disjoint coordinates
Stijn Hawinkel, Wangjun Hu, Britta Velten, Steven Maere
Autocorrelation-aware bivariate Moran's I, bivariate Gaussian process tests and generalized additive models (R package sbivar) test cross-modality colocalisation on disjoint coordinates; many existing permutation tests inflate false positives.
bioRxiv · Jul 23, 2026 · PreprintBioinformatics✦ In-depth digest