Heike Sprenger

Cell line identity rather than medium composition determines transcriptomic profiles of HepaRG and HuH7 cells cultured in chemically defined or serum-based media: comparison with primary human hepatocytes

This study compares transcriptomic profiles of HepaRG and HuH7 cells cultured in chemically defined or serum-based media, finding that cell line identity, not medium composition, is the main determinant of transcriptomic variance.

High-resolution transcriptional atlas of growing maize shoot organs throughout plant development under well-watered and drought conditions

The paper generates a high-resolution spatiotemporal transcriptome dataset of maize shoot organs under well-watered and drought conditions, revealing conserved and organ-specific gene regulation patterns.

Predicting yield traits of individual field-grown Brassica napus plants from rosette-stage leaf gene expression

The paper links rosette-stage gene expression in Brassica napus to field-grown plant yield traits by analyzing individual plants in the field.

Using single-plant -omics in the field to link maize genes to functions and phenotypes

This study profiles individual maize plants in the field to link genes to functions and phenotypes, showing field data can predict gene function and plant traits as effectively as lab data.