Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewed
Single Cell Analysis of Treatment-Resistant Prostate Cancer: Implications of Cell State Changes for Cell Surface Antigen Targeted Therapies
Samir Zaidi, Jooyoung Park, Joseph Minhow Chan…·Charles L. Sawyers
The paper uses single-cell analysis to study how cell surface antigen expression changes in treatment-resistant prostate cancer, revealing transcriptional heterogeneity and shared gene regulatory networks between NEPC and SCLC.