Author

Talal El Zarif

Brigham and Women's HospitalORCID 0000-0002-4507-2396Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Matthew L. FreedmaniD· 3 shared Amin H. NassariD· 2 shared Chris LabakiiD· 2 shared David A. BrauniD· 2 shared Eliezer M. Van AlleniD· 2 shared Jacob E. BerchuckiD· 2 shared Sabina SignorettiiD· 2 shared Sarah Abou AlaiwiiD· 2 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

Matthew L. FreedmanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 7, 2025

EED Maintains the Small Cell Lung Cancer Neuroendocrine Phenotype and Drives Lung Cancer Histological Transformation

Yixiang Li, Yasmin Nabil Laimon, Hyeonseo Cho…·Matthew G. Oser

This study shows EED inactivation impairs SCLC tumorigenesis and drives LUAD-to-SCLC transformation, highlighting its role in maintaining SCLC neuroendocrine identity.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

GenomicsCell ReportsPeer-reviewedJun 1, 2024

Epigenomic signatures as circulating and predictive biomarkers in sarcomatoid renal cell carcinoma

Talal El Zarif, Karl Semaan, Marc Eid…·Sylvan C. Baca

The paper identifies epigenomic signatures in sarcomatoid renal cell carcinoma (sRCC) that predict response to immune checkpoint inhibitors and are detectable in plasma, enabling non-invasive diagnosis.

30 citationstop 2%

humanDNA methylation

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintApr 10, 2022

Germline variants associated with immunotherapy-related adverse events

Stefan Groha, Sarah Abou Alaiwi, Wenxin Vincent Xu…·Alexander Gusev

This study identifies three germline variants associated with immune-related adverse events in patients treated with immune checkpoint inhibitors.

DOI 10.1101/2022.04.10.22273627

humanGWAS summary statistics

𝕏 PostBluesky