Author

Wenxin Vincent Xu

Harvard UniversityORCID 0000-0002-8450-2037Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Toni K. ChoueiriiD· 2 shared Ziad BakounyiD· 2 shared Alexander GuseviD· 1 shared Alexandra–Chloé VillaniiD· 1 shared Amin H. NassariD· 1 shared Ananthan SadagopaniD· 1 shared Andrew Lachlan SchmidtiD· 1 shared Biagio RicciutiiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Toni K. ChoueiriORCID

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2 papers

Recent·Most cited

Dual Inhibition of CDK4/6 and mTORC1 Establishes a Preclinical Strategy for Translocation Renal Cell Carcinoma

Shikha Gupta, Prateek Khanna, Eddy Saad, Renée Maria Saliby, Shatha AbuHammad, Jiao Li, Bingchen Li, Prathyusha Konda, Usman Ali Ahmed, Ananthan Sadagopan, Qingru Xu, Ziad Bakouny, Wenxin Vincent Xu, Ramaprasad Srinivasan, Toni K. Choueiri, Srinivas R. Viswanathan

This study identifies CDK4/6 and mTORC1 pathway activation in tRCC and shows that their dual inhibition synergistically suppresses tRCC cell growth in vitro and xenografts in vivo.

bioRxiv · Jul 11, 2025 · PreprintCancer Biology

Germline variants associated with immunotherapy-related adverse events

Stefan Groha, Sarah Abou Alaiwi, Wenxin Vincent Xu, Vivek Naranbhai, Amin H. Nassar, Ziad Bakouny, Elio Adib, Pier Vitale Nuzzo, Andrew Lachlan Schmidt, Chris Labaki, Talal El Zarif, Biagio Ricciuti, Joao V. Alessi, David A. Braun, Sachet Ashok Shukla, , Alexander Gusev

This study identifies three germline variants associated with immune-related adverse events in patients treated with immune checkpoint inhibitors.

medRxiv · Apr 10, 2022 · PreprintGenetic & Genomic Medicine