GenomicsProceedings of the National Academy of SciencesPeer-reviewed
A Global Analysis of Mutations Accompanying Microevolution in the Heterozygous Diploid Pathogen Candida albicans
Iuliana V. Ene, Rhys A. Farrer, Matthew P. Hirakawa…·Richard J. Bennett
This study analyzes mutations in Candida albicans during microevolution, finding that de novo substitutions and LOH events drive short-term evolution, while purifying selection is strong during host infection.
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