Author

Thorben Sauer

University Hospital Schleswig-HolsteinORCID 0000-0002-4511-6037Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:gene regulatory network inference· 2 Approach:machine learning (classical)· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Timo GemolliD· 3 shared Admar VerschooriD· 1 shared Antje Rackisch· 1 shared Axel Kuenstner· 1 shared Carolin GragolliD· 1 shared Caroline GruneriD· 1 shared Christian FrerkeriD· 1 shared Christoph KnosallaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMolecular Biology

Timo GemollORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintOct 7, 2026

Sphingolipid-Driven Lipotoxicity Promotes Calcific Aortic Valve Disease Through ER-Stress-NF-κB-EndMT Signaling and Is Therapeutically Targetable Through Serine Palmitoyltransferase Inhibition

Elias Rawish, Timo Rusack, Peter Ruben Letsch…·Christian Frerker

This study identifies ceramide-driven lipotoxicity as a driver of calcific aortic valve disease and shows that SPT inhibition can reverse disease progression in vivo.

DOI 10.64898/2026.10.07.757226

humanmouse

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Cancer BiologyCancer Cell InternationalPeer-reviewedMar 27, 2026

Proteomic Remodeling During Tumor Cell-Induced Platelet Aggregation Unveils Metastatic Drivers in Colorectal Cancer

Thorben Sauer, Caroline Gruner, Katharina Kern…·Timo Gemoll

This study identifies proteomic changes in platelets and tumor cells during tumor-induced aggregation in colorectal cancer, revealing proteins linked to metastasis and EMT.

DOI 10.1186/s12935-026-04282-7

humanproteomics

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Molecular BiologybioRxivPreprintApr 9, 2025

Impact of Single Freeze-Thaw Cycles on Serum Protein Stability: Implications for Clinical Biomarker Validation Using Mass Spectrometry

Thorben Sauer, Martina Oberländer, Regina Maushagen…·T. Gemoll

This study assesses the impact of a single freeze-thaw cycle on serum protein stability using mass spectrometry, finding significant abundance changes for 30 proteins, with 11 validated as potential biomarkers for pancreatic disease.

1 citation

humanproteomics

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