Author

Debashis Mukhopadhyay

Saha Institute of Nuclear PhysicsORCID 0000-0002-4516-2260Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Brijesh Kumar SinghiD· 1 shared Debajyoti Das· 1 shared Kaushik ChandaiD· 1 shared Nihar Ranjan JanaiD· 1 shared Partha ChakrabartiiD· 1 shared Piyali MajumderiD· 1 shared Russa DasiD· 1 shared Sampa BiswasiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperNeuroscience

Brijesh Kumar SinghORCID

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3 papers

Recent·Most cited

Aβ42 facilitates the activation of Discoidin Domain Receptor 2 and Its nuclear enrichment in Alzheimer's Disease Model

Russa Das, Sampa Biswas, Debashis Mukhopadhyay

This study shows Aβ42 activates DDR2 in Alzheimer's disease models by non-canonically bypassing collagen ligands and promotes its nuclear enrichment, with structural insights into the mechanism and potential therapeutic inhibition.

Biochemistry · Oct 30, 2026Peer-reviewedBiochemistry

XIST Self-regulates its Association with THOC2 and the Nuclear Epigenetic Machinery via miR-186 in Alzheimer's disease

Somenath Sen, Debashis Mukhopadhyay

This study identifies XIST as a driver of female-specific Alzheimer's disease pathology through a novel regulatory axis involving miR-186, EZH2, and THOC2.

Cell Communication and Signaling · Sep 23, 2026Peer-reviewedNeuroscience

Transcriptional regulator PAX4 links Receptor Tyrosine Kinases and cytoskeleton stability in Alzheimer's disease and type 2 diabetes

Piyali Majumder, Kaushik Chanda, Debajyoti Das, Brijesh Kumar Singh, Partha Chakrabarti, Nihar Ranjan Jana, Debashis Mukhopadhyay

This study identifies PAX4 as a key regulator linking Receptor Tyrosine Kinases and cytoskeletal stability in Alzheimer's disease and type 2 diabetes.

bioRxiv · Jan 26, 2020 · PreprintNeuroscience