This study identifies the USP18-STAT2 axis as a critical factor enhancing hepatic resilience under proteotoxic stress by modulating interferon signaling and ISG solubility.

Cell Communication and Signaling · Oct 29, 2026Peer-reviewedCell Biology

Glucose-dependent regulation of hepatic adipsin controls glucose uptake and tolerance

Sujay Krishna Maity, Asmita Bhar, Abhishek Sen, Tanusree Das, Atin Sasmal, Souveek Mitra, Abhijit Chowdhury, Partha Chakrabarti

This study identifies hepatic adipsin as a glucose-responsive protein that regulates glucose uptake and tolerance through post-transcriptional mechanisms.

Molecular Medicine · Sep 5, 2026Peer-reviewedCell Biology

Deubiquitinase JOSD1 tempers hepatic proteotoxicity

Saheli Chowdhury, Abhishek Sen, Debajyoti Das, Partha Chakrabarti

This study identifies JOSD1 as a deubiquitinase that mitigates hepatic proteotoxicity by stabilizing SOCS1 and enhancing cell survival under proteasome inhibitor stress.

Cell Death Discovery · Sep 16, 2024Peer-reviewedCell Biology

Genomic surveillance and phylodynamic analyses reveal emergence of novel mutation and co-mutation patterns within SARS-CoV2 variants prevalent in India

Nupur Biswas, Priyanka Mallick, Sujay Krishna Maity, Debaleena Bhowmik, Arpita Ghosh Mitra, Soumen Saha, Aviral Roy, Partha Chakrabarti, Sandip Paul, Saikat Chakrabarti

The paper analyzes SARS-CoV2 genomic diversity and phylodynamic patterns in India, identifying prevalent clades and mutation dynamics across 2020.

Frontiers in Microbiology · Jul 29, 2021Peer-reviewedGenomics

Transcriptional regulator PAX4 links Receptor Tyrosine Kinases and cytoskeleton stability in Alzheimer's disease and type 2 diabetes

Piyali Majumder, Kaushik Chanda, Debajyoti Das, Brijesh Kumar Singh, Partha Chakrabarti, Nihar Ranjan Jana, Debashis Mukhopadhyay

This study identifies PAX4 as a key regulator linking Receptor Tyrosine Kinases and cytoskeletal stability in Alzheimer's disease and type 2 diabetes.

bioRxiv · Jan 26, 2020 · PreprintNeuroscience