Author

Sampa Biswas

Saha Institute of Nuclear PhysicsORCID 0000-0001-9904-270XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Bikram Nath· 1 shared Debashis MukhopadhyayiD· 1 shared Joyeeta ChakrabortyiD· 1 shared Raghunath ChatterjeeiD· 1 shared Russa DasiD· 1 shared Sayantan LahaiD· 1 shared Shantanab DasiD· 1 shared Soumen Kanti Manna· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 12 mutual co-author links

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1 shared paperBiochemistry

Bikram Nath

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiochemistryBiochemistryPeer-reviewedOct 30, 2026

Aβ42 facilitates the activation of Discoidin Domain Receptor 2 and Its nuclear enrichment in Alzheimer's Disease Model

Russa Das, Sampa Biswas, Debashis Mukhopadhyay

This study shows Aβ42 activates DDR2 in Alzheimer's disease models by non-canonically bypassing collagen ligands and promotes its nuclear enrichment, with structural insights into the mechanism and potential therapeutic inhibition.

DOI 10.1021/acs.biochem.6c00486

humanproteomics

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BiochemistrybioRxivPreprintOct 29, 2025

PEG400 regulates Falcipain 2 activity through an unprecedented allosteric mechanism

Bikram Nath, Subhoja Chakraborty, Sampa Biswas

This study reveals that PEG400 regulates Falcipain-2 activity through an allosteric mechanism, inhibiting small peptide substrates but enhancing hemoglobin degradation.

DOI 10.1101/2025.10.29.685357

humanproteomics

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GenomicsInfection Genetics and EvolutionPeer-reviewedJun 30, 2020

Characterizations of SARS-CoV-2 mutational profile, spike protein stability and viral transmission

Sayantan Laha, Joyeeta Chakraborty, Shantanab Das…·Raghunath Chatterjee

The paper analyzes SARS-CoV-2 mutation profiles, protein stability, and transmission patterns using whole genome sequencing data to identify key variants and their functional implications.

200 citationstop 3%

viruswhole-genome sequencing

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