Carly Guiltinan

Single-cell roadmap of bovine oogenesis and somatic niche interactions during fetal ovarian development

This study creates a single-cell RNA-seq atlas of bovine fetal ovarian development, identifying cell populations and developmental stages, and showing parallels with human fetal ovaries.

Molecular profiling of bovine primordial germ cell specification and migration onset reveals a conserved program in bilaminar disc embryos

This study identifies the timing and location of bovine primordial germ cell specification and migration, revealing conserved molecular features across species.

Three-dimensional culture in a bioengineered matrix and somatic cell complementation to improve growth and survival of bovine preantral follicles

This study shows that 3D PEG hydrogels improve bovine preantral follicle growth compared to 2D culture, and bESCs can differentiate into gonadal somatic cell precursors.

Primed bovine embryonic stem cell lines can be derived at diverse stages of blastocyst development with similar efficiency and molecular characteristics

This study derives primed bovine embryonic stem cell lines from early and full blastocysts with similar efficiency and molecular characteristics, showing they are indistinguishable and expanding available embryos for stem cell establishment.