Author

Uwe Marx

ORCID 0000-0002-4549-138XUnclaimed ORCID profile · follow to get notified of new preprints

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Uwe Marx2 papers

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Gunnar CedersundiD· 3 shared Kajsa P. KanebrattiD· 3 shared Liisa K. ViléniD· 3 shared Peter GennemarkiD· 3 shared Burçak YesildagiD· 2 shared Christian SimonssoniD· 2 shared Felix Forschler· 2 shared Katharina M. S. SchimekiD· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

Gunnar CedersundORCID

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3 papers

Recent·Most cited

Systems BiologyEuropean Journal of Pharmaceutical SciencesPeer-reviewedAug 30, 2026

M4 drug discovery: human drug predictions from integrated preclinical insights exemplified with a GLP1-R agonist

Oscar Silfvergren, Sophie Rigal, Katharina M. S. Schimek…·Gunnar Cedersund

The paper introduces M4 drug discovery, a method that integrates multi-level, multi-timescale, and multi-species data with mechanistic knowledge to predict clinical outcomes of drugs like GLP-1RAs from preclinical data.

DOI 10.1016/j.ejps.2026.107648

Systems BiologybioRxivPreprintMar 27, 2026

An Integrated Analysis of GLP-1R Agonist Mechanisms: Addressing Study Variations in Heterogeneous Cell Systems

Oscar Silfvergren, Sophie Rigal, Katharina M. S. Schimek…·Gunnar Cedersund

This paper integrates GLP-1RA exenatide studies across heterogeneous cell systems to address variability, providing a unified conclusion and predicting inter-study variabilities.

DOI 10.64898/2026.03.25.714139

humanbulk RNA-seq

Systems BiologybioRxivPreprintAug 18, 2021

Integrated experimental-computational analysis of a liver-islet microphysiological system for human-centric diabetes research

Belén Casas, Liisa K. Vilén, Sophie Bauer…·Gunnar Cedersund

The paper develops a computational model of a liver-islet microphysiological system to predict glucose metabolism and translate experimental results to humans.

1 citation

humanstatistical model