Subthalamic deep brain stimulation and chronic dopaminergic therapy enhance free-choice seeking in patients with Parkinson's disease
David Bendetowicz, Gizem Temiz, Nicolas Tempier, Élodie Hainque, Marie‐Laure Welter, Virginie Czernecki, Brian Lau, Carine Karachi, Jérôme Munuera
This study shows that subthalamic deep brain stimulation and chronic dopaminergic therapy increase free-choice preference in Parkinson's disease patients, with STN-DBS affecting the right medial prefrontal cortex-STN network and chronic dopamine levels enhancing sensitivity to intrinsic rewards.
bioRxiv · Jan 4, 2023 · PreprintNeuroscience