Subthalamic deep brain stimulation and chronic dopaminergic therapy enhance free-choice seeking in patients with Parkinson's disease
David Bendetowicz, Gizem Temiz, Nicolas Tempier…·Jérôme Munuera
This study shows that subthalamic deep brain stimulation and chronic dopaminergic therapy increase free-choice preference in Parkinson's disease patients, with STN-DBS affecting the right medial prefrontal cortex-STN network and chronic dopamine levels enhancing sensitivity to intrinsic rewards.