Maia Lina Elizagaray

This study uses single-cell transcriptomics on patient-derived organoids to identify AGRIN as a regulator of metastatic competence in high-grade serous ovarian cancer.

This study shows that CX3CR1+ macrophages are essential for maintaining immune balance and epithelial integrity in the epididymis and testis, with their depletion leading to immune dysfunction and fertility issues.

This study investigates how intercalated cells interact with immune cells to maintain renal immune homeostasis and contribute to autoimmune kidney disease, identifying an IL-33-mediated Treg interaction.

This study shows that chronic inflammation in the epididymis leads to tertiary lymphoid structure formation and autoimmune fertility issues in mice, with similar autoantibodies found in human infertile patients.

This study identifies RAD52 as a target to overcome PARP inhibitor resistance in BRCA2-deficient ovarian cancer by showing its role in DNA repair and demonstrating synergistic effects with PARP inhibitors.

This study investigates the role of proton-secreting cells in epididymitis, showing they modulate immune responses and impair sperm maturation in mice.