Author

Delesa Damena

University of Cape TownORCID 0000-0002-4594-713XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:GWAS summary statistics· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Research Focus:benchmarking· 1 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:fine-mapping· 1 Research Focus:polygenic risk· 1

Frequent Co-Authors

Emile Rugamika ChimusaiD· 3 shared Lemu GolassaiD· 2 shared Denis AwanyiD· 1 shared Francis Edem AgamahiD· 1 shared Hundaol Girma· 1 shared Ntumba E. Kabongo· 1 shared Peter Opiyo KimathiiD· 1 shared Wonderful Tatenda ChogaiD· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 23 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Emile Rugamika ChimusaORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicineFrontiers in GeneticsPeer-reviewedNov 18, 2021

Functional analysis of genome-wide dataset from 17000 individuals identifies multiple candidate malaria resistance genes enriched in malaria pathogenic pathways

Delesa Damena, Francis Edem Agamah, Peter Opiyo Kimathi…·Emile Rugamika Chimusa

The paper identifies 57 and 125 candidate genes for severe malaria resistance using GWAS data from 17,000 individuals, finding enrichment in malaria pathogenic pathways.

8 citations

humanGWAS summary statistics

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BioinformaticsHuman Molecular GeneticsPeer-reviewedOct 25, 2019

Genome-wide heritability analysis of severe malaria susceptibility and resistance reveals evidence of polygenic inheritance

Delesa Damena, Emile Rugamika Chimusa

The paper estimates SNP-heritability of severe malaria susceptibility and resistance across three African populations, finding polygenic inheritance with significant enrichment in protein coding regions.

11 citations

humanGWAS summary statistics

𝕏 PostBluesky

GenomicsBMC Medical GenomicsPeer-reviewedAug 13, 2019

Genome-Wide Association Studies of malaria susceptibility and resistance: progress, pitfalls and prospects

Delesa Damena, Denis Awany, Lemu Golassa, Emile Rugamika Chimusa

This paper reviews progress and challenges in GWAS of malaria susceptibility, highlighting the need for integrative approaches to understand genetic basis of resistance.

35 citations

humanGWAS summary statistics

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