Murti V. Salapaka

Resolving Heterogeneous Mechanical Domains via Physics-Aware Deep Clustering of Single-Molecule Force Spectroscopy Data

This paper introduces a physics-aware deep clustering method to identify heterogeneous folding domains in single-molecule force spectroscopy data, revealing distinct mechanical properties in natural proteins.

Two operational modes of atomic force microscopy reveal similar mechanical properties for homologous regions of dystrophin and utrophin

This study compares the mechanical properties of dystrophin and utrophin fragments using AFM, finding bacterial utrophin is less stiff than insect utrophin, while dystrophin is intermediate.