Systems BiologybioRxivPreprint
Trajectory matching-random walk feasibility sampling for simulating heterogeneous dynamics in mechanistic models
Fatemeh Beigmohammadi, Jordan J.A. Weaver, Solene G.D. Hegarty-Cremer…·Morgan Craig
This paper introduces TM-RWFS, a method to generate heterogeneity in mechanistic models by constraining trajectories between data bounds, showing it efficiently reproduces biological variability.
DOI 10.1101/2025.09.26.678800