Fatemeh Beigmohammadi

The paper explores the balance between model simplicity and complexity in mathematical models of ovarian cancer growth and treatment response, showing that statistical metrics alone are insufficient for capturing biological mechanisms.

This study shows that the H3-K27M mutation alters hematopoietic stem cell dynamics and erythroid differentiation, increasing blood cell numbers despite impaired maturation.

This paper introduces TM-RWFS, a method to generate heterogeneity in mechanistic models by constraining trajectories between data bounds, showing it efficiently reproduces biological variability.