Benchmarking fragmentation-derived artificial cfDNA reference standards
Lotte Cornelli, N.N. Truong, Robin Van Belle, Sofie Roelandt, Aaron De Cock, Joni Van der Meulen, Siebe Loontiens, Nadine Van Roy, Katleen De Preter
This study benchmarks artificial cfDNA generated by fragmentation methods against native cfDNA, finding enzymatic methods better replicate native characteristics.
bioRxiv · Aug 21, 2026 · PreprintGenomics