Author

Nadine Van Roy

Ghent UniversityORCID 0000-0003-0247-2223Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Bram De WildeiD· 2 shared Katleen De PreteriD· 2 shared Tim LammensiD· 2 shared Aaron De CockiD· 1 shared Aleš VíchaiD· 1 shared Andries De KokeriD· 1 shared Angeline Praveena Enton Raj· 1 shared Annelies Van HemelrykiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Bram De WildeORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintAug 21, 2026

Benchmarking fragmentation-derived artificial cfDNA reference standards

Lotte Cornelli, N.N. Truong, Robin Van Belle…·Katleen De Preter

This study benchmarks artificial cfDNA generated by fragmentation methods against native cfDNA, finding enzymatic methods better replicate native characteristics.

DOI 10.64898/2026.08.12.744389

whole-genome sequencingstatistical model

𝕏 PostBluesky

Cancer BiologyCell Death and DiseasePeer-reviewedFeb 25, 2026

Targeting replication stress in neuroblastoma by exploiting the synergistic potential of second generation RRM2 and CHK1 inhibitors

Iris H. Nelen, Soetkin Leys, Sarah-Lee Bekaert…·Kaat Durinck

This study identifies synergistic effects of second-generation RRM2 and CHK1 inhibitors in neuroblastoma and sarcomas, showing enhanced replication stress and apoptosis.

3 citationstop 2%

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsEpigeneticsPeer-reviewedJul 14, 2020

Minimally invasive classification of pediatric solid tumors using reduced representation bisulfite sequencing of cell-free DNA: a proof-of-principle study

Ruben Van Paemel, Andries De Koker, Charlotte Vandeputte…·Bram De Wilde

This study demonstrates that reduced representation bisulfite sequencing of cell-free DNA can accurately classify pediatric solid tumors with high sensitivity.

65 citations

humanDNA methylation

𝕏 PostBluesky