Author

Lotte Cornelli

Ghent UniversityORCID 0000-0001-8926-5950Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:deconvolution· 1 Assay:DNA methylation· 1 Research Focus:trajectory inference· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Katleen De PreteriD· 2 shared Sofie RoelandtiD· 2 shared Aaron De CockiD· 1 shared Celine EveraertiD· 1 shared Edoardo GiuiliiD· 1 shared Joni Van der MeuleniD· 1 shared Kathleen SchoofsiD· 1 shared Leander MeurisiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenomics

Katleen De PreterORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintAug 21, 2026

Benchmarking fragmentation-derived artificial cfDNA reference standards

Lotte Cornelli, N.N. Truong, Robin Van Belle…·Katleen De Preter

This study benchmarks artificial cfDNA generated by fragmentation methods against native cfDNA, finding enzymatic methods better replicate native characteristics.

DOI 10.64898/2026.08.12.744389

whole-genome sequencingstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintNov 27, 2025

A benchmark of DNA methylation deconvolution methods for tumoral fraction estimation using DecoNFlow

Edoardo Giuili, Sofie Van de Velde, Sam Kint…·Katleen De Preter

This study benchmarks DNA methylation deconvolution methods for tumoral fraction estimation in cfDNA, finding CelFiE most accurate and introducing DecoNFlow as a comprehensive pipeline.

DOI 10.1101/2025.11.27.688590

DNA methylationbenchmark study

𝕏 PostBluesky