Venessa T. Chin

Protein Translation Dysregulation and Immune Cell Evasion Define Metastatic Clones in HPV-related Cancer of the Oropharynx

This study identifies mechanisms of immune evasion and metastasis in HPV-related oropharyngeal cancer using single-cell and spatial genomic data, showing dysregulated protein translation and immune pathway suppression in metastatic clones.

Genetic regulation of cell type-specific chromatin accessibility shapes immune function and disease risk

The paper maps chromatin accessibility and genetic variation in immune cells, showing how integrating cell-type-specific data improves disease risk understanding.

Adult-type diffuse gliomas share recurring cell states driven by a common astrocyte-like glioma stem cell population

This study identifies recurring cell states across adult-type diffuse gliomas and reveals a shared astrocyte-like glioma stem cell population driving intratumoural heterogeneity.