b3galt6 knock-out zebrafish recapitulate β3GalT6-deficiency disorders in human and reveal a trisaccharide proteoglycan linkage region
Sarah Delbaere, Adelbert De Clercq, Shuji Mizumoto, Fredrik Noborn, Jan Willem Bek, Lien Alluyn, Charlotte Gistelinck, Delfien Syx, Phil Salmon, Paul J. Coucke, Göran Larson, Shuhei Yamada, Andy Willaert, Fransiska Malfait
This study shows that b3galt6 knock-out zebrafish exhibit human β3GalT6-deficiency disorders, revealing a novel proteoglycan linkage region mechanism.
Frontiers in Cell and Developmental Biology · Dec 10, 2020Peer-reviewedGenetics