Adelbert De Clercq

This study uses zebrafish models to link genetic mutations in type I collagen to phenotypic severity in OI, identifying biomarkers and mechanisms of variability.

This study develops a zebrafish model of thoracic aortic dissection and rupture by knocking out SMAD3 and SMAD6 genes, revealing novel pathways and potential therapeutic targets.

This study shows that b3galt6 knock-out zebrafish exhibit human β3GalT6-deficiency disorders, revealing a novel proteoglycan linkage region mechanism.