AMPKα2 isoform mediates mTORC2 activation by glucose starvation in endothelial cells
Andrey N. Tikhonov, Nikita V. Podkuychenko, Vladimir P. Shirinsky, Asker Y. Khapchaev, Alexander V. Vorotnikov
The paper investigates how AMPKα2 isoform activates mTORC2 during glucose starvation in endothelial cells and finds it is functionally uncoupled from glucose uptake adaptation.
bioRxiv · Dec 12, 2025 · PreprintMolecular Biology