Author

Alexander V. Vorotnikov

National Medical Research Center of CardiologyORCID 0000-0002-1460-971XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrey N. Tikhonov· 2 shared Nikita V. PodkuychenkoiD· 2 shared Asker Y. KhapchaeviD· 1 shared Gennadii A. BaduniD· 1 shared Maria V. Sudnitsyna· 1 shared Polina A. Bogdanova· 1 shared Veronika S. Perelygina· 1 shared Vladimir P. ShirinskyiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersMolecular Biology

Andrey N. Tikhonov

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2 papers

Recent·Most cited

Free fatty acids increase basal glucose uptake by adipocytes leveling it to insulin stimulated uptake

Nikita V. Podkuychenko, Polina A. Bogdanova, Veronika S. Perelygina, Andrey N. Tikhonov, Gennadii A. Badun, Maria V. Sudnitsyna, Alexander V. Vorotnikov

This study shows that free fatty acids increase basal glucose uptake in adipocytes through GLUT4 translocation, but do not affect insulin-stimulated uptake, suggesting a context-dependent role in insulin resistance.

bioRxiv · Dec 13, 2025 · PreprintMolecular Biology

AMPKα2 isoform mediates mTORC2 activation by glucose starvation in endothelial cells

Andrey N. Tikhonov, Nikita V. Podkuychenko, Vladimir P. Shirinsky, Asker Y. Khapchaev, Alexander V. Vorotnikov

The paper investigates how AMPKα2 isoform activates mTORC2 during glucose starvation in endothelial cells and finds it is functionally uncoupled from glucose uptake adaptation.

bioRxiv · Dec 12, 2025 · PreprintMolecular Biology