Optogenetic inhibition of colon epithelium reduces hypersensitivity in a mouse model of inflammatory bowel disease
Sarah A. Najjar, Lindsay L. Ejoh, Emanuel Loeza‐Alcocer, Brian S. Edwards, Kristen Smith, Ariel Y. Epouhe, Michael S. Gold, Brian M. Davis, Kathryn M. Albers
This study inhibits the colon epithelium and primary afferent neurons in a mouse model of IBD to assess their role in pain hypersensitivity, finding both reduce visceral sensitivity.
Pain · Oct 12, 2020Peer-reviewedNeuroscience