TNF Receptor 1 regulates colonic mesenchymal cell diversity and the epithelial stem cell niche.
Safina Gadeock, Nandini Girish, Cambrian Y. Liu, Ying Huang, Barun Das, Tracy C. Grikscheit, D. Brent Polk
This study shows TNFR1 promotes colonic mesenchymal cell diversity and stem cell niche function, with TNFR1 deficiency reducing cell diversity and impairing stem cell maintenance.
Cellular and Molecular Gastroenterology and Hepatology · Jan 1, 2026Peer-reviewedCell Biology