Cancer BiologybioRxivPreprint
Adipocytes in tumour microenvironment promote chemoresistance in TNBC through oxysterols
Alex Websdale, Yusur Al-Hilali, Baek Kim…·James L. Thorne
This study shows adipocytes in the tumor microenvironment promote chemoresistance in TNBC by secreting oxysterols that activate the LXR pathway and increase P-glycoprotein expression.