Author

James L. Thorne

University of LeedsORCID 0000-0002-3037-8528Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

Aleks PonjaviciD· 1 shared Alex WebsdaleiD· 1 shared Amir RahmaniiD· 1 shared Amy Truesdale· 1 shared Baek KimiD· 1 shared Bethany Jill WilliamsiD· 1 shared Giorgia CioccoloniiD· 1 shared Hanne Røberg‐LarseniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Aleks PonjavicORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintAug 26, 2025

Single-molecule flow cytometry

Amir Rahmani, Matthew Christie, Amy Truesdale…·Aleks Ponjavic

This paper introduces single-molecule flow cytometry (smFC) to detect low-abundance membrane proteins with digital precision, revealing previously undetectable distributions in cancer cells.

DOI 10.1101/2025.08.26.672174

humanflow cytometry

𝕏 PostBluesky

Cancer BiologybioRxivPreprintApr 24, 2025

Adipocytes in tumour microenvironment promote chemoresistance in TNBC through oxysterols

Alex Websdale, Yusur Al-Hilali, Baek Kim…·James L. Thorne

This study shows adipocytes in the tumor microenvironment promote chemoresistance in TNBC by secreting oxysterols that activate the LXR pathway and increase P-glycoprotein expression.

DOI 10.1101/2025.04.24.650225

humanmouse

𝕏 PostBluesky