Oligogenic rare variant contributions in schizophrenia and their convergence with genes harboring de novo mutations in schizophrenia, autism, and intellectual disability: Evidence from multiplex families
Jibin John, Prachi Kukshal, Triptish Bhatia A, Ricardo Harripaul, Vishwajit Laxmikant Nimgaonkar, S.N. Deshpande, Bittianda Kuttapa Thelma
The paper identifies inherited rare variants in schizophrenia families, showing enrichment in neurodevelopmental pathways and convergence with genes linked to de novo mutations in schizophrenia, autism, and intellectual disability.
bioRxiv · Nov 12, 2019 · PreprintGenetics