Youngsook Lucy Jung

This paper develops a high-resolution kinematic method to quantify impaired mobility in dystrophic zebrafish larvae, finding significant differences in swimming performance between mutants and wild-types.

This study identifies metabolomic and transcriptomic signatures in Kabuki syndrome patients, revealing altered metabolites and pathways that could serve as biomarkers for early detection.

The paper identifies mutational signatures SBS26 and SBS54 in MMRD tumors that correlate with immune checkpoint blockade response and survival, suggesting their use as prognostic biomarkers.

This study examines how KMT2D mutations affect histone modifications and gene expression in PBMCs from KS patients, identifying altered enhancer activity and transcriptional changes linked to immune and metabolic gene dysregulation.

This study investigates how WT1-mediated transcriptional reprogramming responds to podocyte injury, revealing a repair mechanism that is later suppressed as injury progresses.

This study analyzes chromothripsis in 2,658 cancers using whole-genome sequencing, finding it prevalent across multiple cancer types with complex structural alterations.