Felipe de Souza Leite

This study compares 3D skeletal muscle spheroids (iSMS) with 2D cultures for modeling Duchenne Muscular Dystrophy, finding improved PAX7 expression and altered Notch signaling in iSMS.

This study shows that increasing JAG1 expression in dystrophin-deficient mice improves muscle size, strength, and myofiber number.

This paper develops a high-resolution kinematic method to quantify impaired mobility in dystrophic zebrafish larvae, finding significant differences in swimming performance between mutants and wild-types.