Fabian Braun

The paper develops single-cell damage scores to quantify cellular deterioration in degenerative diseases and applies them to murine and human datasets to identify molecular trajectories of damage.

This study demonstrates that RNAlater preserves kidney biopsies effectively for single nucleus RNA sequencing, proteomics, and histopathology, but not metabolomics.

This study identifies alpha-synuclein accumulation as a mediator of podocyte injury in Fabry disease, showing that targeting SNCA improves lysosomal function beyond enzyme replacement therapy.

This study identifies PCK2 as a biomarker for renal function 12 months after living donor kidney transplantation using proteomic analysis of urinary extracellular vesicles.