Author

Leonidas D. Arvanitis

City Of Hope National Medical CenterORCID 0000-0002-4744-8350Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Chunli YaniD· 1 shared Crystal N. MarconettiD· 1 shared Dan J. RaziD· 1 shared Edgar Gonzalez· 1 shared Evanthia T. Roussos TorresiD· 1 shared Fan Meng· 1 shared Jinhui WangiD· 1 shared Jonathan Castillo· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Chunli YanORCID

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2 papers

Recent·Most cited

Cell of origin alters myeloid-mediated immunosuppression in lung adenocarcinoma

Minxiao Yang, Noah Shulkin, Edgar Gonzalez, Jonathan Castillo, Chunli Yan, Keqiang Zhang, Leonidas D. Arvanitis, Zea Borok, William D. Wallace, Dan J. Raz, Evanthia T. Roussos Torres, Crystal N. Marconett

This study shows that the cell of origin in lung adenocarcinoma affects the immunosuppressive state of the tumor microenvironment, with AT1-derived tumors showing an anti-tumor immune profile and AT2-derived tumors showing immunosuppressive features.

bioRxiv · Jun 19, 2024 · PreprintCancer Biology

Integrated characterization of cell types, states and molecular programs in disseminated appendiceal neoplasms

Linh T. Bui, Xu Cao, Jinhui Wang, Fan Meng, Mingye Feng, Leonidas D. Arvanitis, Rifat Mannan, Yanghee Woo, Kamran Idrees, Nicholas E. Banovich, Mustafa Raoof

This study uses scRNA-seq to identify cell types and molecular programs in appendiceal neoplasms, revealing cancer-specific cell states and tumor microenvironment interactions.

bioRxiv · Sep 28, 2023 · PreprintGenomics