Author

Mingye Feng

City Of Hope National Medical CenterORCID 0000-0002-3334-9917Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Abdul-Akim GuseinoviD· 1 shared Alba Bundo· 1 shared Alicia Yue· 1 shared Andhika Bintang MahardhikaiD· 1 shared Angela J. RusselliD· 1 shared Changzhong Jin· 1 shared Cheng ZhangiD· 1 shared Christa Elisabeth MülleriD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Abdul-Akim GuseinovORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mechanism of GPR84 allosteric modulation at a helix 8-proximate site

Xuan Zhang, Abdul-Akim Guseinov, Laura Jenkins, Jingkai Zhou, Fabian Gossen, Pinqi Wang, Zobaer Al Mahmud, Yueming Li, Andhika Bintang Mahardhika, Christa Elisabeth Müller, Mingye Feng, Angela J. Russell, Irina G. Tikhonova, Graeme Milligan, Cheng Zhang

This paper identifies a helix 8-proximate allosteric site in GPR84 and shows how it enables Gi-biased signalling through structural and dynamic mechanisms.

Science Advances · Sep 23, 2026Peer-reviewedBiochemistry

Multispecific nanobody degraders co-deplete membrane receptors and enable targeted delivery of diverse payloads

Md Kabir, Yong Joon (Jeffrey) Kim, Zhijie Deng, Yufei Xiang, Paul R. Sargunas, Nuozi Song, Zishan Wang, Nesteene Joy Param, Changzhong Jin, Zhe Sang, Alicia Yue, Alba Bundo, Razeen Hossain, Yue Zhong, Yindan Lin, , Yi Shi

This paper develops MINDS, a multispecific nanobody-Fc platform that co-depletes membrane receptors and delivers diverse payloads, showing improved antitumor activity in cancer models.

bioRxiv · May 6, 2026 · PreprintCancer Biology

Integrated characterization of cell types, states and molecular programs in disseminated appendiceal neoplasms

Linh T. Bui, Xu Cao, Jinhui Wang, Fan Meng, Mingye Feng, Leonidas D. Arvanitis, Rifat Mannan, Yanghee Woo, Kamran Idrees, Nicholas E. Banovich, Mustafa Raoof

This study uses scRNA-seq to identify cell types and molecular programs in appendiceal neoplasms, revealing cancer-specific cell states and tumor microenvironment interactions.

bioRxiv · Sep 28, 2023 · PreprintGenomics