Physics-Informed Digital Twin Can Predict Cerebral Blood Flow and Cerebral Vascular Regulation Mechanisms in Neurocritical Care Patients
Jennifer K. Briggs, J.N. Stroh, Soojin Park, Brandon P. Foreman, Michael M. Tymko, Jay M. J. R. Carr, Melike Sirlanci, Philip Neil Ainslie, Richard K.P. Benninger, Tellen D. Bennett, David J. Albers
This paper introduces CereBRLSIM, a digital twin that predicts cerebral blood flow and CVR mechanisms in neurocritical care patients with higher accuracy than machine learning models.
bioRxiv · May 22, 2025 · PreprintBioengineering