Stress Granule Formation Drives ZBP1-dependent Necroptosis in Non-obstructive Azoospermia and Aging testes
Hongen Lei, Dianrong Li, Jie Chen, Baowen Du, Kaiju Jiang, Tao Xu, Hu Han, Weiliang Fan, Long Tian, Xiaodong Wang
The paper identifies a stress granule-driven necroptosis pathway involving ZBP1 and RIPK3 as a driver of non-obstructive azoospermia and age-related testicular degeneration.
bioRxiv · Apr 11, 2025 · PreprintMolecular Biology