Xiaodong Wang

The paper identifies a stress granule-driven necroptosis pathway involving ZBP1 and RIPK3 as a driver of non-obstructive azoospermia and age-related testicular degeneration.

This study reveals a two-step liquid-to-solid phase transition mechanism by which SARM1 activation leads to axonal degeneration, with implications for therapeutic development.

This study identifies LRG1 as a pro-inflammatory factor in atherosclerosis by promoting macrophage M1 polarization through ERK and JNK pathways, and shows that LRG1 inhibition reduces atherosclerosis progression.

This study shows that necroptosis in testes accelerates aging of the male reproductive system in mice by promoting cellular deterioration.