Erda Qorri

DeltaMut provides a large database of AlphaFold2-predicted missense variant structures to improve variant effect prediction.

This study evaluates normalization and filtering strategies for circRNA differential expression analysis, finding that edgeRs filterByExpr() and linear-aware normalization improve performance.

pLM-SAV predicts pathogenic SAVs using delta-embeddings from protein language models, achieving high performance on labeled data and improving ambiguous predictions over AlphaMissense.

The paper uses bulk and single-cell RNA sequencing to identify senescence-associated biomarkers in canine mesenchymal stem cells across passages.

This study shows nimodipine reduces microglial activation in vitro by altering gene expression and functional phenotypes.