Microbiome impact of ibezapolstat and other Clostridioides difficile infection relevant antibiotics using humanized mice
Trenton M. Wolfe, Jinhee Jo, Nick V. Pinkham, Kevin W. Garey, Seth T. Walk
This study compares the microbiome effects of ibezapolstat and other antibiotics in humanized mice, finding that ibezapolstat and fidaxomicin had smaller impacts on gut microbiome diversity than vancomycin and metronidazole.
Antimicrobial Agents and Chemotherapy · Feb 25, 2025Peer-reviewedMicrobiology