Seth T. Walk

The paper identifies glycine-conjugated indole-3-carboxylates as AHR ligands, showing human-specific activation and microbial/host-mediated metabolism.

This study compares the microbiome effects of ibezapolstat and other antibiotics in humanized mice, finding that ibezapolstat and fidaxomicin had smaller impacts on gut microbiome diversity than vancomycin and metronidazole.

This study uses human intestinal organoids to show microbial colonization induces complex physiological changes in immature human epithelium, including antimicrobial peptide production and mucus maturation.