Thu Nguyen

The paper fine-tunes AlphaFold using high-resolution MHC-peptide crystal structures to improve prediction accuracy for MHC-peptide complex structures, outperforming existing methods in RMSD and lDDT scores.

This study enhances AlphaFold for predicting phosphopeptide-protein complex structures, achieving higher accuracy in lDDT scores for peptides.

The paper introduces a multi-factor clustering method to classify diffraction data from dynamic proteins into polymorphs, using unit cell constants and intensities to cluster mixed-state data from chymotrypsinogen crystals.