Drude SILCS-Nucleic: Harnessing Explicit Electronic Polarization in Targeting RNA and DNA for Drug Design
Haley M. Michel, Anne M. Brown, Alexander D. MacKerell, Justin A. Lemkul
This paper extends the SILCS method with the Drude polarizable force field to improve ligand-nucleic acid interaction modeling and drug design.
Nucleic Acids Research · Sep 4, 2026Peer-reviewedBiophysics