Genome-wide association analyses identify variants in IRF4 associated with acute myeloid leukemia and myelodysplastic syndrome susceptibility
Junke Wang, Alyssa Clay‐Gilmour, Ezgi Karaesmen, Abbas Rizvi, Qianqian Zhu, Li Yan, Leah M. Preus, Song Liu, Yiwen Wang, Elizabeth A. Griffiths, Daniel O. Stram, Loreall Pooler, Xin Sheng, Christopher A. Haiman, David Van Den Berg, , Lara E. Sucheston‐Campbell
This study identifies IRF4 variants associated with increased risk of de novo AML and MDS through GWAS and TWAS analyses using the DISCOVeRY-BMT cohorts.
Frontiers in Genetics · Jun 17, 2021Peer-reviewedGenomics